Principal Investigator
Daniele Ramazzotti
B.Sc., M.Sc., Ph.D.
Associate Professor, Department of Medicine and Surgery
University of Milano-Bicocca, Italy
Daniele Ramazzotti is the founder and director of the Translational Bioinformatics Laboratory (TBL). His work focuses on deciphering cancer evolution, mutational mechanisms and multi-omics heterogeneity, leveraging computational and statistical approaches to advance translational medicine.
Overview
Short biography Career timeline Selected grants Awards & fellowships Patents External profiles & CV
Short biography
Daniele received his Bachelor’s degree in Computer Engineering from Politecnico di Milano and his Master’s degree and Ph.D. in Computer Science from the University of Milano-Bicocca. During his doctoral and postdoctoral training he held research positions at leading international institutions, including:
- Stanford University (Postdoctoral Scholar, 2016–2019)
- New York University, Courant Institute of Mathematical Sciences (Visiting Scholar)
- Cold Spring Harbor Laboratory (Research Intern, Trotman Laboratory)
- Massachusetts Institute of Technology, ALFA Group (Visiting Student)
- Yahoo! Labs Barcelona (Intern, Web Mining Research Group)
In March 2022 he joined the Department of Medicine and Surgery at the University of Milano-Bicocca as a tenure-track researcher and, since March 2025, he is Associate Professor. He leads the Translational Bioinformatics Laboratory, focusing on the development of methods and tools to analyse large-scale genomic, multi-omics and clinical data in oncology and haematology.
Career timeline
- 2016–2019 Postdoctoral Scholar in Biomedical Data Science and Genetics, Stanford University.
- 2022 Joined the Department of Medicine and Surgery at the University of Milano-Bicocca as a tenure-track researcher.
- 2023–2025 Principal Investigator or co-PI on competitive grants including PRIN 2022, PRIN PNRR and Ricerca Finalizzata.
- 2025 Promotion to Associate Professor and consolidation of the Translational Bioinformatics Laboratory (TBL).
- 2026 Awarded a My First AIRC Grant (MFAG 2025) by Fondazione AIRC for Cancer Research.
- 2026 Senior/contact author of a NEJM Evidence study introducing ProgEvo and IPSS-M-Evo, an evolution-informed prognostic score for myelodysplastic syndromes.
Selected grants
-
Ricerca Finalizzata 2024 – Young Researcher
Grant: 450,000 EUR · Italian Ministry of Health · 2027–2029 -
My First AIRC Grant (MFAG 2025)
Grant: 500,000 EUR · Fondazione AIRC for Cancer Research · 2026–2030 -
PRIN PNRR 2022 – Young Researcher
Grant: 236,436 EUR · Italian Ministry of University and Research · 2023–2025 -
PRIN 2022 – Young Researcher
Grant: 259,184 EUR · Italian Ministry of University and Research · 2023–2025 -
Ricerca Finalizzata 2019 – Young Researcher
Grant: 450,000 EUR · Italian Ministry of Health · 2020–2025 -
University Starting Grant
Grant: 115,000 EUR · University of Milano-Bicocca · 2020–2023 -
BRCA Foundation Young Investigator Award
BRCA Foundation · 2018–2019 -
Innovation in Cancer Informatics (ICI) Discovery Grant
Brown Performance Group · 2017
Awards & fellowships
- "Paladini Italiani della Salute" award, 2nd Edition (2024), for the work "Evolutionary signatures of human cancers revealed via genomic analysis of over 35,000 patients".
- Young Talents Award, University of Milano-Bicocca (2020)
- Best interdisciplinary research paper awards (2014, 2016) from the Department of Computer Science, Systems and Communication, University of Milano-Bicocca
- 10th OSS World Challenge (2016–2017), team TRONCO-PiCnIc
- Postdoctoral fellowship, Italian Ministry of University and Research
- Ph.D. scholarship, Italian Ministry of University and Research
Patents
-
2024 – PCT/IB2025/061016
“Integration of Evolutionary, Molecular and Clinical Data for Prognostic Modelling of Clinical Outcomes in Neoplastic Diseases”.
Inventors: D. Ramazzotti, A. Graudenzi, I. Civettini.
Owners: University of Milano-Bicocca and Università Vita-Salute San Raffaele. -
US Patent US11205519B2
“Methods, computer-accessible medium and systems to model disease progression using biomedical data from multiple patients”.
Inventors: D. Ramazzotti et al.
Owners: University of Milano-Bicocca and New York University.
External profiles & CV
A full CV and updated publication list are available through the following links: